Tumor Cell Expression

Cancer, Cell Signalling, Oncology, Vascular endothelial growth factor (VEGF)

Tumor Cell Illustration

Cancers that can express VEGF (Vascular endothelial growth factor) are able to grow and metastasize. Solid cancers cannot grow beyond a limited size without an adequate blood supply. VEGF is a sub-family of growth factors, specifically, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature).

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